cbfβ inhibitor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T22195	CBFβ Inhibitor	5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine	DNA/RNA Synthesis
	CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.		DNA/RNA Synthesis
T4687	Ro5-3335	CBFβ-Runx1 inhibitor II,Ro 5-3335	DNA/RNA Synthesis
	Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins (IC50 = 1.1 μM). Ro5-3335 represses RUNX1/CBFβ-dependent transactivation ...		DNA/RNA Synthesis
T9016	AI-10-47	1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-AI-10-47	Others
	AI-10-47 (1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-AI-10-47) is a small molecule inhibitor of CBFβ-RUNX binding(IC50 : 3.2 μM).		Others
T6753	AI-10-49		DNA/RNA Synthesis
	AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.		DNA/RNA Synthesis
T24550	NSC-140873	GCPK
	NSC-140873 is the RUNX1-CBFβ interaction inhibitor.
T69678	WUN40378
	WUN40378 is compound first reported in PCT Int. Appl. (2019), WO 201909959, in which it was described as CBFβ-RUNX1 inhibitor. WUN40378 is very similar to Ro 5-3335 but with an F instead of Cl. WUN40378 is also analog of...